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10.1186/1940-0640-8-21 36.Comer SD , Sullivan MA , Vosburg SK , et al

[22] [23] Baseline assessment should be considered before initiating tirzepatide in high-risk patients, including those over 65 years of age, individuals with pre-existing gastrointestinal disorders, patients on concurrent metformin or acid-suppressing medications, and those following restrictive diets

10.1158/1535-7163.mct-17-0697 278 ZhangY.DingM.WangL.YinS.ZhangL.CaoX.et al (2023)

One possible role of folate in mental health is its action on DNA methylation and gene expression which have been wildly reported in human psychiatric disorders