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Likewise, corneal neovascularization might be induced by hypoxic conditions (upregulation of proangiogenic factors, downregulation of anti-anxiogenic factors to supply oxygen to the cornea) [181]

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This study also suggested the protective effect NR supplementation had on alcohol-induced liver injury, whose mechanism could involve the gut microflora-bile acid axis

Hepatology 57, 555565 (2013)
