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PD typically progresses slowly, with non-motor symptoms often appearing years before motor symptoms, leading to delayed diagnosis (151)

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10.1111/febs.16110 [DOI] [PubMed] [Google Scholar] Mao C, Liu X, Zhang Y et al (2021) DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer

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We observed that the classic strategies including co-expression of molecular chaperones and fusion expression with solubilizing tags are ineffective in improving its solubility