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Toward, R., Montandon, S., Walton, G

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and Singh, N

These C-terminal domain studies examine the classic structure-activity finding of GHRH(1-29) equivalence to GHRH(1-44) , testing whether this equivalence holds across the full range of pharmacodynamic endpoints relevant to physiological GHRHR biology or whether the C-terminal extension contributes subtle but pharmacologically significant differences in receptor interaction characteristics under conditions not captured by acute in vitro activity assays

2 Materials and methods 2.1 Study population This study utilized a randomized controlled design involving 62 patients with acute ischemic stroke admitted to the Department of Neurology between August 2020 to October 2022, meeting specific inclusion and exclusion criteria