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Chen et al., (87), showed in their work that alcohol consumption leads to hepatic acrolein accumulation and a decrease in glutathione-s-transferase-Pi (GSTP) that helps to metabolize acrolein

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From intermediates 2b and 3b , we were also able to demonstrate that the biosynthetic enzymes (MurCMurF, Fig

, Xu X., Li M., Cai J., Wei Q., and Niu H