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As mentioned in the section above, IDH1 catalyzes typically the conversion of isocitrate to -KG, but the mutant isoform converts -KG into D-2HG instead, which has been shown to inhibit cellular differentiation through epigenetic alterations [19]
Two separate populations of mitochondria exist in myelinated axons, stationary and motile mitochondria
S1PR3 deficiency alleviates radiation-induced pulmonary fibrosis through the regulation of epithelialmesenchymal transition by targeting miR-495-3p
He wanted five separate city departments to go after dog owners for the maximum $100 fine, to make examples of scofflaws
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