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Anyone with Digestive Issues or Absorption Problems: People with gastrointestinal conditions like Crohns disease, IBS, or those who have had bariatric surgery may struggle to absorb B12 through food alone and could benefit from supplementation
Nevertheless, a lot of these are not believed to be virtually as absorbable as natural animal resources are

When deficiency is suspected based on clinical features (fatigue, paraesthesia, cognitive changes) or risk factors (vegan diet, gastric surgery, certain medications), serum B12 measurement guides appropriate intervention

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