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These findings confirmed that M

Site-directed mutagenesis experiments show that cysteine-553 in human GLCLC is involved in heterodimer formation between the catalytically active GLCLC and the auxiliary, activity-enhancing GLCLR unit, which likely occurs through a disulfide bond [139]

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For instance: (i) GSH synthesis is a two-step process mediated by cytosolic enzymes (a faster process with respect to a gene-mediated one)

In this review, based on the current literature, the influence of micronutrients and the effectiveness of selected types of diets in the treatment of HT were assessed