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However, taking extremely high doses may cause acne, rashes, or place stress on the kidneys in certain cases
J Mass Spectrom 48:2441
Contractor R, Samudio IJ, Estrov Z, Harris D, McCubrey JA, Safe SH, Andreeff M , Konopleva M
[DOI] [PubMed] [Google Scholar] 159.Lyle B.J., Mares-Perlman J.A., Klein B.E., Klein R., Greger J.L
However, the currently used DNMT inhibitors have limitations (an inconsistent demethylation response and high toxicity level during prolonged use), which can be potentially overcome by using combined anti-cancer therapies
