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Usually released by our liver, think of it as an antioxidant produced in our body

The well-known tumor suppressor protein p53 has been implicated in the intricate regulation of ferroptosis

For example, vitamin D induces BDNF release via calcium signaling by upregulating voltage-gated calcium channels, while folate and B vitamins are involved in neuroprotective effects through limiting neurotoxic homocysteine levels, which inhibits neurotrophic signaling [221]

In contrast, ALP and GGT are membrane-bound glycoprotein enzymes

In vitro , GSH-deficient hepatocytes show upregulated mRNA levels of DNA methyltransferase, Tet2, and Tet3, along with increased Dnmt activity (5-mC) and global DNA methylation levels