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Sala V., Gallo S., Gatti S., et al

In mammalian cells, Bcl-2 associated X protein (BAX) is recruited when various endogenous and exogenous stimuli induce apoptosis and form pores in the mitochondrial membrane [41], facilitating the release of Cyto-C (as a well conserved electron-transport protein and a part of the respiratory chain localized in mitochondrial intermembrane space.) into the cytoplasm

This can be achieved to a large extent by successful nutritional management

Fluorescence-guided high-grade glioma surgery more than four hours after 5-aminolevulinic acid administration

Besides, suppressing of IGF1R both leads to ATM kinase inactivation and inhibited DNA-PKcs phosphorylation, which are involved in the DNA repair of NHEJ (Chitnis et al., 2014)