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A phase 3 trial of olezarsen treatment for 53 weeks is underway and is expected to be completed by 2023 (NCT0456-8434)

Y., Nunez D., Ramachandran A., Anaya-Cisneros M., Tian R., Lefer D

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So if a supplement is being used thoughtfully, the expectation should usually be: consistent use enough time repeat assessment when clinically indicated Not panic after two weeks