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Phenotypic and functional changes in monocytes with ageing and after HIV infection Monocytes play a central role in innate immunity and are classified into three subpopulations: Classical (CD14CD16), intermediate (CD14CD16), and nonclassical (CD14 low CD16), each with distinct functions in antigen presentation, cytokine secretion, and tissue surveillance [42, 43]

Shannon B, Gnanasampanthan S, Beilby J, Iacopetta B

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