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Adv Exp Med Biology

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In our recent work ( The observed negative correlation between 5-HIAA and BDNF in our pediatric patients ( Table 3 ) leads us to speculate that 5-HIAA may negatively affect the maintenance and survival of neurons and synaptic plasticity regulated by BDNF ( Information on NEO and BIO levels in depressed children and adolescents is only sporadic and quite heterogeneous

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Hypopituitarism patterns among adult males with prolactinomas

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Control: control group with saline at the same volume

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Cuadrado and colleagues first showed that GSK-3 inhibits NRF2 activity, but the identification of sites in NRF2 that are phosphorylated by GSK-3 was achieved several years later using two-dimensional electrophoresis and mass spectrometry: GSK-3 phosphorylates a group of Ser residues at the level of DSGIS motif in the Neh6 domain of NRF2, and this event represents the signal for the recognition by the adapter protein -TrCP, that targets NRF2 for ubiquitination and proteasomal degradation in a KEAP1-independent manner [150, 151]

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