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10.1016/j.canlet.2023.216307

In the process, superficial hyperpigmented cells begin to die, to make way for new cells formed in the skins matrix, resulting in lighter-looking skin

This is accompanied by a decrease in OXPHOS that is characterized by blunted TCA cycle and reduced mitochondrial respiration

4 Analysis of important natural compounds Since pharmacotherapy based on a single target has been insufficient for drug development in complex diseases, the emerging multi-target approach is a promising strategy for the search of new drug candidates

Low red blood cell counts (anemia) due to vitamin B12 deficiency
