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Vitamin B12 deficiency can suppress the symptoms of polycythemia vera

The authors concluded that due to the high prevalence of MTHFR variants and how crucial it is to assure pregnant women get adequate supplementation, L-methylfolate may be the best option to avoid blood folate deficiencies. The study also notes that excessive ingestion of folic acid could mask an undiagnosed B12 deficiency, and that it was unlikely that methylfolate would mask a B12 deficiency in the same way

Research shows increased lifespan in animal models, delayed onset of age-related diseases, and improved immune competence with combined use