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These compounds include gallic acid, 3,4-dihydroxyphenylacetic acid, 4-hydroxybenzoic acid, p-coumaric acid, vanillic acid, ferulic acid, (-)-epicatechin, neochlorogenic acid, procyanidins, proanthocyanidins B1 and B2, an A-type trimer, scopoletin, and (E)-chlorogenic acid (also known as caffeylquinic acid, caffetannic acid, helianthic acid, and igasuric acid) (458)

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doi: 10.2174/187153009789044392 [DOI] [PubMed] [Google Scholar] 81

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Clinical studies have highlighted these variations in encapsulation efficiency, underscoring the need for careful formulation and optimization in liposome-based drug delivery