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It functions as a potent antioxidant, a cofactor for enzymatic reactions, and a crucial modulator of immunity (Singh and Jain 2022)
Nature 454 , 10091013 (2008)

Most individuals with significant hypercholesterolemia do not have classic monogenic autosomal dominant inherited dyslipidemias, but polygenic factors contributing to susceptibility to environmental factors underlie the observed increase in LDL-C levels
