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This increase was statistically significant in both groups (Sig

If G binds to the T 5 helix of the TIM barrel-like domain, the same orientation effects could occur, but there may also be a significant allosteric component to activation because this helix contacts two autoinhibitory elements, the XY linker and H 2 helix (Fig

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It is also important to note that many of the proteins that are associated with LNPs might not be the result of conventional protein corona formation, but rather specific interactions that drive the assembly of LNP-protein aggregates/fusion

Busuttil S, Abela J, Pace GJ: Support vector machines with profile-based kernels for remote protein homology detection