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A detailed history is obtained to assess risk factors, including sun exposure, family history, and skin type

The spots were developed using an AEC substrate set (551951, BD Bioscience, USA)

& Quaglia, D

PLoS Biol 11 , e1001648 (2013)

2.1 Changes in Inflammatory Cells, Proinflammatory Factors and Growth Factors 2.1.1 Increased Inflammatory Cells and Proinflammatory Factors Generally, wound healing is a process mediated by growth factors and cytokines released by different cells (Davis et al., 2018) such as fibroblasts, endothelial cells, phagocytes, platelets, and keratinocytes (Davis et al., 2018) activated by the immune response after the skin barrier is broken