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Inflammatory cytokines, such as tumor necrosis factor alpha (TNF) and interleukin6 (IL6), have been shown to impair insulin signaling and glucose uptake in muscle and adipose tissue and to promote hepatic gluconeogenesis and lipolysis

By employing mild autoclave treatment and fermentation, the researchers demonstrated that tobacco leaves can be converted into ethanol with significantly reduced greenhouse gas emissions and energy consumption compared to traditional lignocellulosic fuels

Mori J, Patel VB, Ramprasath T, Alrob OA, Desaulniers J, Scholey JW, et al

The ratio of pro-inflammatory to anti-inflammatory cytokines, particularly the IL6-to-IL10 ratio, serves as a biomarker for follicular inflammatory status [271, 272]

Mutations in the genes encoding surfactant proteins [surfactant protein C (SFTPC) and A2 (SFTPA2)] can lead to abnormal surfactant folding and ERS, and promote epithelial-mesenchymal transition (Mulugeta et al., 2015