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A prespecified analysis of the SELECT trial revealed that patients assigned to once-weekly subcutaneous semaglutide 2.4mg lost significantly more weight than those receiving placebo and showed improvements in various anthropometric indices.

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Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) is a master regulator of oncogenic signaling, uniquely catalyzing the isomerization of phosphorylated Ser/Thr-Pro motifs to drive malignant transformation, proliferation, and metastasis