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The model posits that dopaminergic hyperactivity is an indirect consequence of the reduced number of parvalbumin inhibitory interneurons in the hippocampus and the PFC (Lodge and Grace 2008

Influence of Estrogenic Metabolic Pathway Genes Polymorphisms on Postmenopausal Breast Cancer Risk

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In cancer cells, CHAC1 has been shown to influence the response to chemotherapy by modulating redox homeostasis and contributing to the induction of cell death pathways
Klyubin I, Betts V, Welzel AT, Blennow K, Zetterberg H, Wallin A, Lemere CA, Cullen WK, Peng Y, Wisniewski T, Selkoe DJ, Anwyl R, Walsh DM, Rowan MJ
