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Sanders, S

Reduced glutathione also known as glutathione or GSH is found in all living systems.[1] Lowered tissue GSH levels have been observed in several disease conditions.[2] The restoration of cell GSH levels in a number of these conditions have proven to be beneficial

The following databases were searched: Ovid MEDLINE, MEDLINE In-Process and Other Non-Indexed Citations, Ovid Embase, Wiley Cochrane, EBSCO Cumulative Index to Nursing & Allied Health Literature (CINAHL), and Centre for Reviews and Dissemination/International Agency for Health Technology Assessment

This may be due in part to the fact that alanine does not function as an intracellular osmolyte in astrocytes, whereas glutamine does perform this function

J Clin Oncol 27(15s):376s, 2009