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A well-characterized target of PKA targets is CREB

10.3390/ijms231710045 23 HsuC

In addition to its role in energy metabolism, creatine appears to act as a buffer against the harmful effects of reactive oxygen species in cardiovascular tissues, potentially slowing the progression of cardiovascular disease [110], although this is a topic that deserves further investigation as not all evidence shows benefits of higher intracellular levels of creatine [111]

Benvenga S, Ruggeri RM, Russo A, et al

The majority of the body's choline is found in specialized fat molecules known as phospholipids, the most common of which is called phosphatidylcholine (1)