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Genetic nicotinamide N-methyltransferase (nnmt) deficiency in male mice improves insulin sensitivity in diet-induced obesity but does not affect glucose tolerance

The supplement group had significantly greater improvements than the placebo group on the Parental Global Impressions-Revised (PGI-R, Average Change, p = 0.008), and on the subscores for Hyperactivity (p = 0.003), Tantrumming (p = 0.009), Overall (p = 0.02), and Receptive Language (p = 0.03)

Data are unavailable on the toxicity of other preservatives in this age group

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