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These compounds indirectly benefit the eyes by protecting critical fatty acids from oxidation

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Kiruthiga PV, et al

doi: 10.1126/sciadv.aav0184 5 ChenL.ZhangZ.HoshinoA.ZhengH

Importantly, ZSWIM8 binding appears incompatible with conformations observed for AGO2miRNA complexes not engaged with a TDMD trigger, as the PAZ and N domains would either clash with or fail to contact ZSWIM8 (refs