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Preclinical studies in rodents have shown an association between GLP-1 receptor activation and thyroid C-cell changes, although a direct causal link in humans has not been established, and UK/EU SmPCs for authorised GLP-1 RAs do not list MTC or MEN2 as a formal contraindication
Shi L, Zhang Z, Yu AM et al (2014) The SLE transcriptome exhibits evidence of chronic endotoxin exposure and has widespread dysregulation of non-coding and coding RNAs
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Effects of SIRT1 gene knock-out via activation of SREBP2 protein-mediated PI3K/AKT signaling on osteoarthritis in mice
