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Transporters can mediate passage of molecules in the blood-to-brain direction or can mediate removal of solute (eg, waste products) from brain-to-blood (Pardridge, 2015a)
We find individuals with accelerated heart aging have a 250% increased heart failure risk and accelerated brain and vascular aging predict Alzheimers disease (AD) progression independently from and as strongly as plasma pTau-181 (ref

However, in this study, the cisplatin Pt@Au@FeNPs, despite having activity at nanomolar concentrations, were cross-resistant with cisplatin in A2780/cp70 cells (Figure 5C)

[DOI] [PubMed] [Google Scholar] 19.Guan KL, Dixon JE

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