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Together, these finding indicate that the toxic effects of DOX on the heart are strongly associated with iron overload and ferroptosis in mitochondria, indicating that targeting ferroptosis could serve as a promising therapeutic strategy for protecting the hearts of cancer patients from DOX-induced cardiomyopathy
Wie sicher ist Glutathion
doi: 10.1016/j.mcn.2010.02.006 34
Curr Opin Hematol 2002
Zinc shows a multilayered function in the nucleus, ranging from structural support, enzymatic catalysis, epigenetic and transcriptional regulation, signaling, genome maintenance and redox balance
