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*Correspondence: Mohamed Ashraf Virmani, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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This would suggest that the neuroprotective properties of either enantiomer of huperzine do not have a direct relationship to their AChE inhibitory activities

Summary: Berberine and L-carnitine can be taken together as no direct interactions are documented, but evidence for their combined use is limited and neither is recommended in UK clinical guidelines

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