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Integrative clinical and preclinical studies identify FerroTerminator1 as a potent therapeutic drug for MASH
99, 11031113.10.1111/j.1471-4159.2006.04152.x 69 KasischkeK
This characteristic renders flavonoids particularly suitable as immunomodulatory agents for chronic inflammatory disorders, especially for long-term maintenance therapy during the early or remission phases of the disease

The expression of IL-4, IL-13, and IL-4 receptor (IL-4R) is upregulated in prurigo nodules, with IL-4 correlating with the intensity of itch (8, 11, 26, 27)