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It establishes cellular antioxidant defense by transcriptionally activating antioxidant genes (e.g., SOD2, CAT, GCL) and reductive molecules (e.g., GSH, Trx), while downregulating pro-oxidant molecule synthesis, thereby directly scavenging or neutralizing excess ROS [134]

doi: 10.1096/fj.14-253633

2001;280(1):L69L78

We showed that the association between family conflict and a clinical diagnosis of mood and anxiety disorders only started to emerge in adults but not in adolescents, which implies that relevant interventions to ameliorate family conflict might be a preventive measure against the future development of mood and anxiety disorders in the young populations

NakamotoY.SudaT.MomoiT.KanekoS.2004Different procarcinogenic potentials of lymphocyte subsets in a transgenic mouse model of chronic hepatitis B