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Upregulation of cytokines (IFN-, IFN-, IFN-, IL-8, and IL-12) expression was observed in the spleen, while cecal tonsils were characterized by downregulation of IL-6, IL-2, and IL-8 post-hatch

It was well known that, under physiological conditions, the NRF2/HO-1 axis is essential for resistance to oxidative stress, and upregulation of this axis significantly suppresses the expression of NLRP3, caspase-1, and ASC, inhibits inflammasome formation, blocks GSDMD activation, and prevents the release of IL-1 and IL-18

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10.1016/j.celrep.2019.02.037 119 LuT.LiM.ZhaoM.HuangY.BiG.LiangJ.et al (2021)
Ambar RF, Agarwal A, Majzoub A, et al
