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lab is further supported by the Thyssen Foundation (10.19.2.025MN) and the German Cancer Aid (70112888)
The therapeutic goals of B 12 treatment are the reversal of metabolic abnormalities and the prevention or reduction of clinical symptoms (fig 1)
Nature 485, 195200
Lipopolysaccharides activate pain receptors in trigeminal sensory neurons (207)
By contrast, those with the MTHFR A1298C CC genotype (homozygous mutant) tend to have higher folate concentrations without overt clinical symptoms, although vitamin B12 deficiency may be masked (63)
