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Description
Like other type I proteins that traverse the lipid bilayer, the lipid-spanning portion of the peptide would be predicted to adopt an alpha-helical secondary conformation, a secondary structure characterized by every amino acid interacting with the 4th amino acid beyond, the so-called i + 4 rule of alpha-helical protein conformations

Convenience and simplicity

[DOI] [PubMed] [Google Scholar] Buchanan M

This process is essential for the proper folding and stability of numerous proteins, including enzymes, hormones, and structural proteins like collagen

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