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doi: 10.1371/journal.pone.0105504, 26
The second commonly used representative model for assessing cellular responses to particulate exposure is the murine macrophage cell line RAW264.7
The NRF2 pathway is regarded as the most important system controlling antioxidant defense in vivo, which can resist oxidative stress damage
This modularity permits context-dependent tuning, enabling autophagy to function as a dynamic rheostat instead of a binary switch
Koga, T
