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Paracrine Regulation and Microenvironment Melanocytes are known to be closely associated with keratinocytes and fibroblasts, as they secrete many factors that modulate the function of melanocytes, reduce oxidative damage, and maintain their survival

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Zhang, J., Wang, L., Wang, H., Su, Z

Complementary in vitro assessments further indicate that luteolin exhibits minimal cytotoxicity toward non-malignant cells at concentrations typically required for anti-inflammatory or antioxidant actions, supporting a favorable biological response profile (Tuli et al., 2022)
