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The function of this regulation is to allow rapid response to oxidative challenge by increasing the formation of glutathione, a process dependent on cysteine availability (Figure 2)

ALS/FTD-linked TBK1 deficiency in microglia induces an aged-like microglial signature and drives social recognition deficits in mice

However, the protective effect diminished after PI3K inhibitors were administered
Sci Rep 12:3922

Comparisons with other percutaneous techniques, such as radiofrequency and microwave ablation (MWA), highlight CAs favorable safety profile [25, 26]
