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As a result of the disarrayed F-actin at the luminal and basal ends of the cell, and the separation of occludin, ZO-1, and ZO-2 from the membrane of lateral TJs, C

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Since peptide helicity is essential for their biological functions, the incorporation of DMSO poses a critical limitation in characterizing peptide drugs

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Based on the in vivo experiment in the ICV-STZ rat model of AD, modulation of the PI3K/Akt/GSK3 signaling pathway could diminish oxidative stress, neuro-inflammation, and apoptosis, Moreover, amyloid plaque number and phosphorylated tau expression were marked decrement (Nishizaki, 2018)