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Furthermore, several metabolites, such as bilirubin and melatonin, have antioxidant effects [60, 61]

[DOI] [PMC free article] [PubMed] [Google Scholar] 73.Bissig M, Hagenbuch B, Stieger B, Koller T & Meier PJ Functional expression cloning of the canalicular sulfate transport system of rat hepatocytes

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Bastian SE, Walton PE, Wallace JC, Ballard FJ. Plasma clearance and tissue distribution of labelled insulin-like growth factor-I (IGF-I) and an analogue LR3IGF-I in pregnant rats. J Endocrinol. 1993 Aug;138(2):327-36.doi: 10.1677/joe.0.1380327. PMID: 7693845

Reported Effects Weight reduction (no diabetes): In REDEFINE 1, CagriSema 2.4 mg + 2.4 mg produced roughly 22.7% mean weight loss at 68 weeks (trial-product estimand), though this fell short of the ~25% Novo Nordisk had guided toward [1]