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[Article in Danish]

Raw and processed data have been deposited in NCBIs GEO database (GSE291472)

Apart from visual problems, i.e., retinitis pigmentosa and/or optic atrophy, and hearing loss, this cohort of 13 unrelated patients also had other clinical features such as hypotonia, global developmental delay, axonal sensorimotor polyneuropathy, regression after febrile illness, ataxia, failure to thrive, progressive microcephaly, and encephalopathy [85]

Using cell death kinetic analysis, gene-editing and metabolic tracing, we show that inhibition of RNR-dependent nucleotide metabolism allows for conservation of intracellular GSH and a reduction in ferroptosis susceptibility in cancer cells

Pasture assignments were also balanced by dietary treatment group