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Nrf2 is associated with apoptosis and DNA repair Numerous reports suggest that oxidative stress induces cell apoptosis, and antioxidants, such as increased levels of HO-1, protect the cell against apoptosis

Hippo coactivator yap1 upregulates sox9 and endows esophageal cancer cells with stem-like properties

25 In addition to the conventional protein targets mentioned above, certain genetic regions can be utilized for therapeutic intervention

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