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80 On the other hand, individuals who self-report having depression or anxiety are twice as likely to have irritable bowel syndrome as those reporting no mood problems

In the intestine, a portion of glutathione is cleaved by the enzyme gamma-glutamyltransferase (GGT) into its amino acid components: glutamate, cysteine, and glycine

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To measure the levels of NLR family pyrin domain-containing protein 3 (NLRP3), apoptosis-associated speck-like protein containing a C-terminal caspase recruitment domain (ASC), and caspase-1 in lysates, ELISA kits from MyBioSource (San Diego, CA, USA) were used for this assay, and all procedures followed manufactures instruction

This action has a defense function that prevents harmful substances from entering the intestinal barrier [1] The intestinal barrier forms two complex layers, which consist of an apical barrier and basolateral barrier (Figure 1)