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doi: 10.1007/s00405-021-06725-5 117 ChaabanMCoreyJP

In conclusion, an imbalance in redox reactions is only one of the many factors contributing to ASD, and further studies are necessary to investigate other factors, such as impaired neurotransmission, immune dysregulation in the brain, and mitochondrial dysfunction

NAD infusion therapy is often used with the goal of supporting mitochondrial function and cellular metabolism, although clinical outcomes may vary [4] Why NAD+ Levels Decline With Aging Aging places increasing demands on cellular repair mechanisms

Oleocanthal Oleocanthal (Oc), a dialdehydic derivative of decarboxymethyl elenolic acid bound to Tyr, ( p -HPEA-EDA) was shown in vitro to inhibit both COX-1 and COX-2, inflammatory enzymes involved in the biosynthesis of inflammatory prostaglandins in a dose-dependent manner, and to be more effective than ibuprofen in inhibiting these enzymes at equimolar concentrations [260] (see Figure 1)

Toxicol Lett 2011;204:7180
