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THERAPEUTIC STRATEGIES FOR WD Current pharmacological approaches Current treatment approaches aim to reduce systemic copper burden either by limiting intestinal copper absorption through zinc-induced metallothionein-mediated sequestration of copper within enterocytes or by enhancing urinary copper excretion using chelators such as D-penicillamine and trientine [4]
doi: 10.1038/s41388-022-02329-3
Recent studies discovered their role in mucosal immunity tolerance and maintenance of intestinal barrier integrity
doi:10.1038/s41419-019-2025-z
