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Editorial comment on: Antioxidant treatment associated with sildenafil reduces monocyte activation and markers of endothelial damage in patients with diabetic erectile dysfunction: a double-blind, placebo-controlled study

Furthermore, persistent neuroinflammation is associated with pathological ROS production, likely due to NF-B activation by redox signaling, including involvement of NOX2 (97)

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Further, human populations, which have a significant reduction in CPT1A activity, have been found to have a decreased prevalence of CNS diseases such as multiple sclerosis and ALS 20,21
