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That matters because connective tissues remodel slowly

Similarly, a study by Zhou et al

Opposing effects of interferon-gamma on iNOS and interleukin-10 expression in lipopolysaccharide- and mycobacterial lipoarabinomannan-stimulated macrophages

A more ambiguous role is played by GPx8, which inactivates SERCA, but due to the reduction of the ER Ca 2+ reservoir, also reduces ER-mitochondria Ca 2+ flux 11

Pathogens 10 (2), 211
