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Males represented 81.4%

BaP induced significant hypermethylation of the DKK2 and EN1 gene promoter elements, and then inhibited DKK2 and EN1 gene expression, which promoted lung cancer cell proliferation and cancer development

Indo-1 fluorescence signals were measured 2 h after treatment with PMA (100 nM), A23187 (1.25 M) or PMA in the presence of BAPTA-AM (25 M) ( n = 3) ( e ), and quantification of intracellular Ca 2+ levels in PS-exposed (Annexin V + ) versus non-exposed (Annexin V ) cells at 2 h following PMA stimulation ( n = 3) ( f )

MacDonald JA, Bothun AM, Annis SN, Sheehan H, Ray S, Gao Y, et al

10.1016/j.jhep.2015.08.014 54 KhalilN.ManganasH.RyersonC