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(Sun et al., 2022) illustrated that NNMT knockdown in a low-glucose environment enhanced the NAD + /NADH ratio in U251 glioma cells

HHcy activates the release of inflammatory factors, induces leukocyte chemotaxis and activation, and causes ER stress

RSC Med Chem 12:12541261
Most older adults dont need a B12 supplement Older adults should not take B12 supplements unless they have a documented deficiency, Yourman says and only about 20 percent of adults over age 60 do, according to a report from the American Academy of Family Physicians

Some studies suggest it may even help prevent cognitive decline
